Gargoylism with cardiovascular involvement in two brothers.

The term " Gargoyle" was introduced by Ellis, Sheldon, and Capon in 1936. The condition was first recognized by Thomson in 1900, but his original cases were not reported until later (Henderson and Ellis, 1940). Although about 200 cases have been reported, there are few detailed studies of the cardiovascular system. Necropsy material is rare, and has been reviewed by Strauss (1948) and Lindsay (1950). Since then other necropsies have been reported by Jervis (1950), Magee (1950), Henderson et al. (1952), Millman et al. (1952), Schwarz (1952), and Smith et al. (1952), making a total of 32 in all. The following observations were made on two brothers, both with gargoylism, who were studied during life and found to have cardiovascular involvement. One died and the post-mortem findings are reported.